Ta'lim innovatsiyasi va integratsiyasi

DRUG ALLERGIC REACTIONS: CURRENT VIEWS (REVIEW)

BAKHROMOVA BARNO ZOKIROVNA

ALIBAYEVA YULDUZ RAHMANOVNA

MUMINBOYEV DIYORBEK JASURBEK OGLU

Keywords: Key words: drug allergy; diagnosing drug allergy; drug hypersensitivity reactions.

---

Abstract

More than 7% of population suffer from drug allergy. Cases of heavy life-
threatening allergic reactions are well known. In this review current considerations of
mechanisms of drug immune hypersensitivity development are presented, the main
clinical forms and methods of diagnosing drug allergy are described. Drug allergy is
diagnosed with specific in vivo tests (skin prick test, intradermal test, patch test,
provocation tests) and in vitro tests (determination of specific IgE to medications, test
for basophil activation, reactions of leucocyte blast transformation, quantitative
determination of cytokines and other proteins, e.g. granzyme and tryptase in peripheral
blood). However, not all of these methods are available in real clinical practice, the list
of commercial kits for diagnosis of drug allergy is limited. Therefore, it is especially
important in patient management to rely on history-taking and general clinical
examination data, to consider the available information on association of drug allergy
and infections caused by viruses of herpes-group, especially in children population, on
hereditary predisposition to some kinds of drug allergy.

---

References

References

Meliqulov, O. J., & Ernazarova, M. S. (2022). DORI VOSITALARINING

BARQARORLIGINI OSHIRISH YO’LLARI. Oriental renaissance: Innovative,

educational, natural and social sciences, 2(Special Issue 4-2), 978-982.8-9

Meliqulov, O. J., & Kodirov, N. D. (2022). 1.4-BENZODIAZEPINNING

TIBBIYOTDA QO'LLANADIGAN VOSITALARI. Oriental renaissance:

Innovative, educational, natural and social sciences, 2(8), 313-317.

Meliqulov, O. J., & Baymuradov, E. S. (2022). VITAMIN B12 NING OLINISHI

VA UNING AHAMIYATI. Oriental renaissance: Innovative, educational,

natural and social sciences, 2(8), 324-327.

Меликулов, О. Ж., Кодиров, Н. Д., & Баймурадов, Э. С. (2022).

ИСПОЛЬЗОВАНИЕ БАРБАРИСА В ФАРМАКОТЕРАПИИ. Oriental

renaissance: Innovative, educational, natural and social sciences, 2(Special Issue

-2), 911-913.

Mirzoyeva, F. A., Imamova, Y. A., & Meliqulov, O. J. (2022). MEDICINAL

PLANTS AND THEIR PROPERTIES. Web of Scientist: International Scientific

Research Journal, 3(4), 1140-1144.

Meliqulov, O.J., & Baymuradov, E.S. (2022). VITAMIN B12 NING OLINISHI

VA UNING AHAMIYATI. Oriental renaissance: Innovative, educational, natural

and social sciences, 2 (8), 324-327.

Эрназарова, М. Ш., & Бахромова, Б. З. (2022). Исследования свойств

лекарственных растений содержащих алкалоид. Science and Education, 3(11),

-116.

Нажмитдинов, Х. Б., Олимов, С. М., & Бахромова, Б. З. (2022). ПОЛЕЗНЫЕ

СВОЙСТВА ФРУКТА–ПЕРСИК. Oriental renaissance: Innovative,

educational, natural and social sciences, 2(9), 327-332.

Baxromova, B. Z., & Ernazarova, M. S. (2022). Dorivor lavanda o’simligi haqida

umumiy ma’lumot va uning tibbiyotda qo’llanilishi. Science and Education, 3(11),

-95.

Shernazarovna, E. M., & Zokirovna, B. B. (2023). KAMQONLIK SABABLARI

VA UNI TABIIY YO’L BILAN DAVOLASH CHORALARI. ОБРАЗОВАНИЕ

НАУКА И ИННОВАЦИОННЫЕ ИДЕИ В МИРЕ, 15(1), 160-165.

Shernazarovna, E. M., Zokirovna, B. B., & Shuxrat o’g’li, D. B. (2023). RAYHON

O’SIMLIGIGA UMUMIY TAVSIF. ОБРАЗОВАНИЕ НАУКА И

ИННОВАЦИОННЫЕ ИДЕИ В МИРЕ, 15(1), 166-168.

Shernazarovna, E. M., & Zokirovna, B. B. (2023). YALPIZ (MENTHA)

O’SIMLIGINING DORIVOR XUSUSIYATLARI. ОБРАЗОВАНИЕ НАУКА И

ИННОВАЦИОННЫЕ ИДЕИ В МИРЕ, 15(1), 169-172.

Olimov, S. M., & Baxromova, B. Z. (2022). ZANJABIL HAQIDA UMUMIY

MA'LUMOT. TIBBIYOTDA QO'LLANILISHI. Journal of new century

innovations, 14(1), 156-160.

Shernazarovna, E. M., & Zokirovna, B. B. (2023). QANDLI DIABET

KASALLIGI VA UNING ASORATLARI. Journal of new century

innovations, 26(4), 116-121.

Бахрамова, Б. З., Эрназарова, М. Ш., & Муминбоев, Д. Ж. (2023).

ОТНОШЕНИЕ ЧЕЛОВЕКА К ПРИРОДЕ И ОТНОШЕНИЕ ПРИРОДЫ К

ЧЕЛОВЕКУ. ББК 30.16 Б 63, 89.

Bakhromova, B., & Mo’minboyev, D. (2023). THE LIFE OF ABU ALI IBN SINA

AND HIS CONTRIBUTION TO THE FIELD OF PHARMACY. Бюллетень

педагогов нового Узбекистана, 1(9), 39-42.

Baxramova, B., & Mo’minboyev, D. (2023). SHIFOBAXSH ZANJABILNING

TIBBIYOTDA QO'LLANILISHI. Центральноазиатский журнал образования

и инноваций, 2(9), 86-89.

Baxramova, B., Xolbo’tayeva, K., & Mo’minboyev, D. (2023). BIOLOGIK FAOL

MODDALARNING INSON SALOMATLIGIGA TA’SIRI. Инновационные

исследования в науке, 2(9), 5-8.

Zokirovna, B. B., & Khusan, K. (2023). VALERIAN ROOT IN THE

TREATMENT OF SLEEP PROBLEMS AND RELATED DISORDERS-A

SYSTEMATIC REVIEW AND METAANALYSIS. Journal of Modern

Educational Achievements, 10(1), 21-27.

Бахрамова, Б., & Муминбоев, Д. (2023, September). ОТНОШЕНИЕ

ЧЕЛОВЕКА К ПРИРОДЕ И ОТНОШЕНИЕ ПРИРОДЫ К ЧЕЛОВЕКУ.

In Международная конференция академических наук (Vol. 2, No. 9, pp. 9-13).

Yuldashev, S., Halimbetov, Y., Usmanova, M., Naimova, Z. S., & Khamraeva, M.

(2021). National Processes In Uzbekistan And The Formation Of The

Internationalist Maturity Of The Younger Generation. The American Journal of

Medical Sciences and Pharmaceutical Research, 3(06), 167-175.

.Хасанова, Г. Р., & Усмонова, М. Б. (2022). Применение фасоли (phascolus) в

медицине. Science and Education, 3(11), 117-125.

Sh, A., Kuylieva, M. U., & Usmanova, M. B. (2022). Application of phytotherapy

in the treatment of chronic prostatitis. Web of Scientist: International Scientific

Research Journal, 3(5), 466-470.

Sh, A., Kuylieva, M. U., & Usmanova, M. B. (2022). Application of phytotherapy

in the treatment of chronic prostatitis. Web of Scientist: International Scientific

Research Journal, 3(5), 466-470.

Имамова, Ю. А., & Усманова, М. Б. (2022). РОДИОЛЫ РОЗОВАЯ ДЛЯ

ПОВЫШЕНИЯ РАБОТОСПОСОБНОСТИ ОРГАНИЗМА. Oriental

renaissance: Innovative, educational, natural and social sciences, 2(Special Issue

-2), 901-904.

.Имамова, Ю. А., Усманова, М. Б., & РОДИОЛЫ, Р. ORIENSS. 2022. №

Special Issue 4-2. URL: https://cyberleninka. ru/article/n/rodioly-rozovaya-dlya-

povysheniyarabotosposobnosti-organizma.

Усманова, М. Б., & Имамова, Ю. А. (2022). ЛУК РЕПЧАТЫЙ–

ПРИМЕНЕНИЕ В МЕДИЦИНЕ. Oriental renaissance: Innovative, educational,

natural and social sciences, 2(Special Issue 4-2), 914-917.

Қўйлиева МУ, Э. М., Усмонова, М., & Имамова, Ю. (2021). General

information on the age of Chilonjtyda, its composition, application in folk

medicine, its features and their different types, conditions for

cultivation. Шкурова, Д., Усманова, М., & Имамова, Ю.

Usmanova, M., & Toshpolatov, C. Endokrine gland system, humoral

managementof the organizm. Researchjet journal of analisis and inventions In

Voiume, 1.

Шкурова, Д., Усманова, М., & Имамова, Ю. (2021). Private technology of

powders Preparation of powders with abrasives, dyes and hard powders, extracts

and essential oils. Экономика и социум,(11), 90.

Usmanova, M., & Yuldoshev, C. Importanse of lipids in the cell, simple and

compleks lipids, classification. Researchjet journal of analisis and inventions.

Imomova, Y., Usmonova, M. B., Yo‘Ldoshev, S., & Ahmadov, J. (2021). DORI

VOSITALARINING ZAMONAVIY TAHLIL USULLARI. Oriental

renaissance: Innovative, educational, natural and social sciences, 1(8), 587-596.

Усманова, М., Эрназарова, М., Куйлиева, М., & Хасанова, Г. (2021).

Дорихона фаолиятини ташкил этиш, дорилар саклаш чора

тадбирлари. Экономика и социум,(11), 90(6).

Хасанова, Г. Р., Усманова, М. Б., & Нажмитдинов, Х. Б. (2022).

ВИТАМИНГА БОЙ ЛОВИЯ (PHASCOLUS) ЎСИМЛИГИНИНГ УМУМИЙ

ХУСУСИЯТЛАРИ. Oriental renaissance: Innovative, educational, natural and

social sciences, 2(9), 333-336.

Xasanova, G. R., Ernazarova, M. E., & SHIFOBASH, Q. O. T. F. J. ORIENSS.

№ Special Issue 4-2. URL: https://cyberleninka. ru/article/n/shifobash-qoqi-

otining-foydali-jihatlari.

Yakubova, Sarvinoz Raxmonqulovna, & Xasanova, Gulbaxor Raxmatullayevna

(2022). KAMQONLIK HAQIDA TUSHUNCHA. Oriental renaissance:

Innovative, educational, natural and social sciences, ( Special Issue 4-2), 897-900.

Mirzoyeva, F. A., Imamova, Y. A., & Meliqulov, O. J. (2022). Medicinal plants

and their properties. Web of Scientist: International Scientific Research

Journal, 3(4), 1140-1144.

Usmanova, M. B. (2022). Geksikon shamchasini tayorlashda uning asosni

almashtirish. Science and Education, 3(11), 213-220