Pathomorphological Characteristics of Renal Changes in Fatal Cases of Preeclampsia: A Comprehensive Analysis
Abstract
Preeclampsia is a significant cause of maternal mortality worldwide, characterized by hypertension and proteinuria after the 20th week of gestation. While renal involvement is a prominent feature of preeclampsia, the exact mechanisms leading to renal failure in severe cases remain unclear. This thesis explores the role of systemic inflammation in renal pathology associated with fatal preeclampsia. By analyzing renal tissue specimens and reviewing the literature, this study aims to provide new insights into how systemic inflammation contributes to renal injury and adverse maternal outcomes. Findings from this research may lead to novel therapeutic strategies to improve the management of preeclampsia and reduce maternal mortality.
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