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Published
2023-11-25
Section
Articles
How to Cite
THE ROLE OF THIOTRIAZOLINE IN THE ORGANISM
Axmedov Shamshod Jamshidovich
Keywords: Keywords: piracetam, thiotrizoline, thiacetam, neuroprotection, neurotrophic effect, contact dermatitis, pneumonia, nitric oxide, thiotriazoline, tiazotic acid (Thiotriazoline), post-COVID syndrome, antiplatelet, anticoagulant, endothelioprotective and hepatoprotective action
Abstract
The paper considers the synergy between the nootropic drug piracetam and the
metabolic agent thiotriazoline that maintains energy metabolism and survival of
neurons and other types of cells. Piracetam, a nootropic drug, a chemical pyrrolidone
derivative, is used in neurological, psychiatric, and narcological practice. There is
evidence on the positive effect of piracetam in elderly and senile patients with coronary
heart disease. This drug is supposed to stimulate redox processes, to enhance glucose
utilization, and to improve regional blood flow in the ischemic brain regions. Due to
its action, the drug activates glycolytic processes and elevates ATP concentrations in
brain tissue. Thiotriazoline is a compound that has antioxidant, anti-ischemic
properties. The co-administration of piracetam and thiothriazoline is an innovation area
in the treatment of stroke and other brain damages, especially in insulin resistance and
high blood glucose levels. The paper considers the neurobiological properties of
thiotriazoline and piracetam, which synergistically exert neuroprotective and
neurotrophic effects.
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